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James Siena has exhibited widely including solo presentations at Pace Gallery (New York), The Print Center (Philadelphia), The Museum of Modern Art (New York), and Dieu Donné (New York). His work is held in numerous prestigious public and private collections including the Hammer Museum (Los Angeles), Herbert F. Johnson Museum of Art, Cornell University (Ithaca, New York), The Metropolitan Museum of Art (New York), Museum of Fine Arts (Boston), The Museum of Modern Art (New York), San Francisco Museum of Modern Art, Whitney Museum of American Art (New York) and Yale University Art Gallery (New Haven).